The molecular underpinnings of learning-related plasticity
Rosa Isabel Caamaño Tubío and her team (Erin Warren) are examining NMDA-mediated learning in the nucleus accumbens, with the aim of discovering the intra-cellular events that lead to learning-related plasticity in nucleus accumbens neurons.Currently, they are examining the effects of intra-nucleus accumbens infusions of an NMDA antagonist drug on the acquisition of a simple tone-food association (conditioned approach paradigm).
Nucleus accumbens coding of reward expectation. Neuropharmacology and electrophysiology.
Veronica Dobrovitsky and her team (Gabriela Canales
and Miguel Briones) are testing the hypothesis that dopamine
transmission at D1 receptors within the nucleus accumbens sets the threshold for
reward expectation (generated by conditioned stimuli associated with varying
probabilities of reward delivery) to generate behavioral approach responses. In
collaborative studies conducted at